In Vivo Scientist

In Vivo Scientist – Cell Therapy and Neurodegeneration

The Company

Mangrove Neuro (LIC, NY) is a well-funded, fast-paced, early-stage biotech company using cell and tissue replacement therapies to treat neurodegeneration and brain trauma. We use a multifaceted approach to designing and testing our prototypes. As an early-stage team member, your data will directly drive our upcoming IND-enabling milestones

The Role

We are seeking a highly motivated, cross-functional In Vivo Scientist to lead the validation of our neural graft prototypes in rodent models. You will oversee the end-to-end surgical, histological, and analytical pipelines, acting as a crucial bridge between our stem cell engineering team and pre-clinical milestones.

Key Responsibilities

- Perform survival stereotaxic surgical procedures in rodents, including graft preparation, tissue harvest, and transplantation.

- Image grafts by confocal and widefield microscopy and quantify cell survival, integration, and phenotype

- Maintain detailed experimental records and contribute to study design and IND-enabling documentation

Qualifications

- PhD with a background in neuroscience, neurodevelopment, stem cell biology, or related fields with 0-2 years of relevant post graduate experience (industry setting preferred)

- Hands-on experience with histology, immunostaining, and fluorescence microscopy

- Rodent brain survival surgery experience

- Ability to work independently and manage multiple experiments in a fast-paced, early-stage setting

- Experience using rodent stroke models and/or behavioral models

- Hands on experience with rat models

- Experience with hiPSC culture

- Quantitative image analysis (Fiji/ImageJ, QuPath, or similar)

- Familiarity with cell therapy development

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Compensation: $110,000 – 135,000 based on experience with great health insurance and equity.

Please apply through this portal or send your CV to ***email_hidden*** with “In Vivo Scientist application” in the subject line.